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The only reliable indicator is reduced biological response in your research model

The most common signs and symptoms are: Muscle tremors Postural instability and impaired balance (difficulty remaining upright especially when standing still or rising from a chair) Difficulty with walking, often taking shuffling (festinating) steps, Slowness of movements (bradykinesia) Inability to get movements going (akinesia) Sustained or repeated muscle cramp (dystonia) Stiffness of muscle movement (rigidity) Stooped posture (due to being postural unstable so then subconsciously lowering ones center of gravity to compensate) Increased postural sway (body motion when standing still) Loss of smell Sleep disturbances

The improved stability of the arginate form has profound implications for study design and potential outcomes

Effects of Ginkgo biloba on Diseases Related to Oxidative Stress